UK - Residential Clinic

Looking for a rehab clinic/treatment centre in the UK area?

You can receive independent, expert advice on alcohol rehabilitation and rehab centres by telephoning directly on 0845 370 0203

The most important consideration in choosing a rehab centre is to match the individual to the rehab centre that is most likely to lead to a successful outcome.

We can provide an assessment of all your needs and a recommendation regarding the most effective rehab placement for you, given your particular circumstances. We can provide fast, immediate access to alcohol treatment.

Rehab News: Drug has potential to prevent alcoholics from relapsing

An experimental drug that blocks the euphoric feelings associated with drinking may prevent alcoholics from relapsing. The finding, the result of a mouse study at Oregon Health & Science University, could lead to human clinical trials within the next year.

"We showed we could block behaviour in mice that resembles this increased euphoria even after the animals had been given a lot of alcohol," said Tamara Phillips, Ph.D., professor and vice chair of the behavioural neuroscience department at OHSU and a research scientist at the Portland Veterans Affairs Medical Center. "That's what you want in a treatment, because we don't get to people until after they become addicted to alcohol."

Earlier research has shown that some people's brains become sensitized as a result of chronic exposure to alcohol. This change in the brain does not subside after people quit drinking. So when they begin consuming alcohol again, "they get a bigger jolt," Phillips said.

Alcohol consumption causes the body to release a substance known as "corticotrophin-releasing factor" or CRF. It activates receptors in the brain. Phillips and her team determined that a brain receptor called CRF1 appears to be involved in this heightened pleasure sensation. They compared the responses of normal mice and mice bred without the CRF1 receptor to chronic doses of alcohol. Mice without the CRF1 receptor did not experience the euphoric jolt the normal mice demonstrated.

The research team also took normal mice with the CRF1 receptor and exposed them to chronic doses of alcohol. Before testing for the euphoric response, the researchers gave the mice an experimental drug called CP 154,526 developed by Pfizer which prevents CRF from reaching the brain receptor. This group of mice also did not experience the heightened reaction.

Phillips' study recently was published in the Proceedings of the National Academy of the Sciences. The results may be particularly applicable to stress-induced relapse. That's because the CRF1 receptor also triggers the body's response to stress.

This could have implications for PTSD patients. "I think if you block this receptor, you might be able to decrease drinking in response to PTSD," Phillips said.

The next step is testing CP 154,526 to see if it is safe for use in humans. If it clears that hurdle, researchers will start human trials to determine if the drug can prevent alcoholic relapse.

Reference: Raul Pastor et al., 'Corticotropin-releasing factor-1 receptor involvement in behavioral neuroadaptation to ethanol: A urocortin1-independent mechanism', PNAS, July 1, 2008 vol. 105 no. 26 9070-9075

Article published on 15/08/2008 by DryOutNow.com

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News

Community projects cut alcohol disorder, shows research

Initiatives to cut alcohol-related disorder problems through community projects have had a 'considerable positive impact' in local areas, shows new research presented at a conference at the ...

Computer Programs Could Help Drug Abusers Stay Abstinent

Drug abusers who used a computer-assisted training program in addition to receiving traditional counselling stayed abstinent significantly longer than those who received counselling alone, a Yale University study has found.

77 people who sought treatment for drug and alcohol abuse were randomly assigned to receive traditional counseling or to get computer-assisted training based on principles of cognitive behavioural therapy as well as sessions with a therapist.

The ...

subjects who received computer-assisted training had significantly fewer positive drug tests at the conclusion of the study, reported Kathleen M. Carroll, professor of psychiatry and lead author of the study.

"We think this is a very exciting way of reaching more people who may have substance use problems and providing a means of helping them learn effective ways to change their behaviour," Carroll said.

Cognitive behavioural therapy concentrates on teaching skills and strategies to help people change behaviour patterns and has been proven to be effective way to treat a wide variety of psychiatric disorders. However, such therapy is not widely available for people with substance use problems, Carroll said.

Also, many counsellors lack the time or training to fully implement cognitive behavioural therapies for their patients, she said. She and her team at the Yale School of Medicine developed a software program to help supplement counselling in drug addiction as well as other psychiatric disorders.

The computer-assisted therapy program consists of text, audio, and videotaped examples designed to help the user learn new ways of avoiding the use of drugs and changing other problem behaviours.

The study volunteers had sought treatment at a substance abuse clinic in Bridgeport, Ct. and met diagnostic criteria for a substance use problem, with alcohol, cocaine, opioids or marijuana. Those assigned to computer-assisted training were exposed to six lessons, or modules, that they accessed from a computer located at the treatment program. Each module included a brief movie that presented a particular challenge to the subjects' ability to resist substance use − such as the offer of drugs from a dealer. The narrator of the module then presented different skills and strategies to avoid drug use and also show videotapes of individuals employing those strategies.

The findings were reported in the May edition of the American Journal of Psychiatry.

Article published on 30/05/2008

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Government of Canada Delivering Critical Treatment Initiatives

The Canadian Government recently announced critical drug treatment initiatives for Canadian provinces and territories under the National Anti-Drug Strategy.

"This investment will provide an important boost to the drug treatment options that are available to young people who are at-risk," said Tony Clement, Minister of Health. "It represents the Government's commitment under the National Anti-Drug Strategy to work with our provincial and territorial counterparts and partners, such as the Canadian Centre on Substance Abuse. Our objective is to improve access to quality services and effective approaches to treating individuals who pose a risk to themselves, their families and their communities."

The Drug Treatment Funding Program (DTFP) is a new federal contributions program under the Treatment Action Plan of the National Anti-Drug Strategy. The DTFP will provide $111 million over five years to provincial and territorial governments to assist in strengthening treatment systems and in filling critical gaps in treatment through investments in early intervention treatment initiatives designed to reduce and eliminate the progression and severity of illicit drug use behaviour among youth.

"We know that drugs are dangerous and destructive. This is why this Government is committed to ensuring that those people who are addicted to illicit drugs get the help they need," said Minister Nicholson. "At the same time, however, we are also being very clear: we will not tolerate those who prey on our youth or profit off of the vulnerability of addicts."

Article published on 20/05/2008

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